Actin antibody (Actin, alpha 1, Skeletal Muscle)

Details for Product anti-ACTA1 Antibody No. ABIN6297627
Antigen
  • ACTA
  • ASMA
  • CFTD
  • CFTD1
  • CFTDM
  • MPFD
  • NEM1
  • NEM2
  • NEM3
  • acta
  • asma
  • cftd
  • cftd1
  • cftdm
  • mpfd
  • nem1
  • AA959943
  • Acta-2
  • Acts
  • Actsk-1
  • actc
  • actc1
  • cfk
  • hm:zeh0631
  • zeh0631
  • acta1
  • actin, alpha 1, skeletal muscle
  • actin, alpha 1, skeletal muscle L homeolog
  • actin, alpha 1b, skeletal muscle
  • actin, muscle
  • actin, alpha skeletal muscle
  • ACTA1
  • acta1.L
  • acta1
  • Acta1
  • acta1b
  • LOC100533357
  • LOC109479779
  • LOC109108280
Reactivity
Human, Mouse (Murine), Rabbit, Rat (Rattus)
217
120
119
30
21
20
14
11
9
8
8
7
6
5
5
4
3
3
2
2
2
1
1
1
1
1
1
Host
Mouse
142
103
Clonality
Monoclonal
Conjugate
This Actin antibody is un-conjugated
18
14
13
5
5
5
3
3
3
3
3
3
Application
Immunohistochemistry (IHC)
179
99
89
64
48
36
14
14
8
3
2
1
1
Options
Purpose Mouse anti-Human/Mouse/Rabbit/Rat Muscle Actin Antibody [IHC only]
Immunogen SDS extract of human myocardium was used as the immunogen for this Muscle actin HHF35 antibody.
Specificity Cytoplasmic
Purification SDS extract of human myocardium was used as the immunogen for this Muscle actin HHF35 antibody.
Plasmids, Primers & others Plasmids, Primers & others Actin products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Actin, alpha skeletal muscle (ACTA1 Antibody Abstract)
Background

Target Description: This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. This mAb recognizes alpha and gamma isotypes of all muscle groups. Nonmuscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of nonmuscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).

Gene Symbol: ACTA1///ACTA

Gene ID 58
UniProt P68133
Pathways Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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