Tumor Necrosis Factor antibody (TNF) (Biotin)

Details for Product anti-TNF Antibody No. ABIN6297805
Antigen
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LOC103694380
  • tnfa
Reactivity
Human
1007
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Host
Mouse
741
510
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2
Clonality (Clone)
Monoclonal ()
Conjugate
This Tumor Necrosis Factor antibody is conjugated to Biotin
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Application
ELISA, Western Blotting (WB)
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Options
Purpose Mouse anti-Human TNF alpha Biotinylated Antibody
Immunogen This antibody was produced by fusion of mouse myeloma with B cells obtained from a mouse immunized with a recombinant protein immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.
Clone 5H4-F10-E11
Isotype IgG3
Plasmids, Primers & others Plasmids, Primers & others Tumor Necrosis Factor products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TNF alpha (TNF Antibody Abstract)
Background

Target Description: TNF alpha is an  adipokine  involved in systemic  inflammation  and is a member of a group of cytokines that stimulate the  acute phase reaction. It is produced chiefly by activated  macrophages  (M1), although it can be produced by many other cell types such asCD4+ lymphocytes,  NK cells, neutrophils, mast cells, eosinophils, and neurons.

UniProt P78536
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus
Application Notes ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)
Restrictions For Research Use only
Reconstitution A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.
Storage 4 °C,-20 °C,-80 °C
Storage Comment -20°C
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