STAT2 antibody (Signal Transducer and Activator of Transcription 2, 113kDa) (Biotin)

Details for Product anti-STAT2 Antibody No. ABIN6297844
Antigen
  • wu:fj84d07
  • p113
  • stat2
  • 1600010G07Rik
  • AW496480
  • ISGF-3
  • P113
  • STAT113
  • signal transducer and activator of transcription 2
  • AGAP000099-PA
  • stat2
  • STAT2
  • Stat2
Reactivity
Human
279
106
97
8
1
1
1
1
1
1
1
Host
Rabbit
298
16
1
Clonality
Polyclonal
Conjugate
This STAT2 antibody is conjugated to Biotin
14
9
9
6
6
6
6
6
6
6
6
6
2
2
2
2
2
1
1
Application
ELISA
244
120
109
47
27
22
8
8
7
6
3
3
3
2
1
1
1
1
1
1
Options
Purpose Rabbit anti-Human Phosphorylated STAT2 Antibody [+Biotin],
Immunogen This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others STAT2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Signal transducer and activator of transcription 2 (STAT2 Antibody Abstract)
Background

Target Description: Signal transducer and activator of transcription 2  is a  protein  that in humans is encoded by the STAT2  gene.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (IRF9), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.STAT2-PY is the phosphorylated form of STAT2 protein.

Gene Symbol: STAT2

Gene ID 6773
UniProt P52630
Pathways JAK-STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
Application Notes ELISA (recommended work dilution= 1:320,000)
Restrictions For Research Use only
Reconstitution Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.
Storage 4 °C,-20 °C,-80 °C
Storage Comment -20°C
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