Peroxisome Proliferator-Activated Receptor alpha (PPARA) antibody

Details for Product No. ABIN6297876
Antigen
  • NR1C1
  • PPAR
  • PPARalpha
  • hPPAR
  • LOC100136415
  • PPARALPHA
  • nr1c1
  • xPPARalpha
  • xppara
  • 4933429D07Rik
  • AW742785
  • Nr1c1
  • PPAR-alpha
  • Ppar
  • peroxisome proliferator activated receptor alpha
  • peroxisome proliferator-activated receptor alpha
  • peroxisome proliferator activated receptor alpha L homeolog
  • PPARA
  • LOC100136415
  • ppara.L
  • Ppara
  • ppara
Reactivity
Human, Mouse (Murine)
196
154
110
11
10
10
9
9
7
6
6
4
3
2
2
2
1
1
1
Host
Mouse
181
50
Clonality
Monoclonal
Conjugate
Un-conjugated
9
5
5
5
5
5
5
5
4
3
2
2
2
2
2
2
2
Application
182
68
55
44
43
28
26
18
12
10
7
6
4
2
2
1
1
Options
Purpose Mouse Anti-PPARA Antibody
Immunogen This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.
Antigen
Alternative Name PPARA (PPARA Antibody Abstract)
Background

Target Description: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

Gene Symbol: PPARA

Gene ID 5465
UniProt Q07869
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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