TRKA antibody (Neurotrophic Tyrosine Kinase, Receptor, Type 1)

Details for Product anti-NTRK1 Antibody No. ABIN6297887
Target
Reactivity
Human, Mouse
304
213
166
2
1
Host
Rabbit
292
31
3
3
1
Clonality
Polyclonal
Conjugate
This TRKA antibody is un-conjugated
24
17
16
14
11
11
11
9
9
9
8
8
7
7
7
7
7
2
2
1
1
Application
187
122
88
75
39
39
23
23
10
8
5
4
4
1
1
Options
Purpose Rabbit Anti-TrkA Antibody
Immunogen This TrkA antibody is generated from rabbits immunized with TrkA his fusion protein
Target
Alternative Name TrkA (NTRK1 Antibody Abstract)
Background

Target Description: TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Gene Symbol: NTRK1

Gene ID 4914
UniProt P04629
Pathways RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)