PAWR antibody
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- Target See all PAWR Antibodies
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAWR antibody is un-conjugated
- Application
- Please inquire
- Purpose
- Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,
- Top Product
- Discover our top product PAWR Primary Antibody
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- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
- Alternative Name
- Prostate Apoptosis Response protein-4 (PAWR Products)
- Synonyms
- MGC81382 antibody, pawrl antibody, zgc:103513 antibody, PAWR antibody, PAR4 antibody, Par-4 antibody, Par4 antibody, 2310001G03Rik antibody, pro-apoptotic WT1 regulator antibody, PRKC, apoptosis, WT1, regulator L homeolog antibody, PRKC, apoptosis, WT1, regulator antibody, PAWR antibody, pawr.L antibody, pawr antibody, Pawr antibody
- Background
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Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
Gene Symbol: PAWR
- Gene ID
- 5074
- UniProt
- Q96IZ0
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