PAWR antibody (PRKC, Apoptosis, WT1, Regulator)

Details for Product anti-PAWR Antibody No. ABIN6298166
Antigen
  • MGC81382
  • pawrl
  • zgc:103513
  • PAWR
  • PAR4
  • Par-4
  • Par4
  • 2310001G03Rik
  • pro-apoptotic WT1 regulator
  • PRKC, apoptosis, WT1, regulator L homeolog
  • PRKC, apoptosis, WT1, regulator
  • PAWR
  • pawr.L
  • pawr
  • Pawr
Reactivity
Human, Mouse (Murine), Rat (Rattus)
88
45
45
7
3
3
3
3
2
2
2
Host
Rabbit
82
5
1
Clonality
Polyclonal
Conjugate
This PAWR antibody is un-conjugated
3
3
3
3
3
3
3
Application
72
44
38
13
4
3
3
3
3
1
Options
Purpose Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,
Plasmids, Primers & others Plasmids, Primers & others PAWR products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Prostate Apoptosis Response protein-4 (PAWR Antibody Abstract)
Background

Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

Gene Symbol: PAWR

Gene ID 5074
UniProt Q96IZ0
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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