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PCMT1 antibody

PCMT1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630131
  • Target See all PCMT1 Antibodies
    PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
    Reactivity
    • 49
    • 21
    • 20
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 44
    • 5
    Rabbit
    Clonality
    • 44
    • 5
    Polyclonal
    Conjugate
    • 26
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCMT1 antibody is un-conjugated
    Application
    • 33
    • 13
    • 13
    • 12
    • 10
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogen
    PCMT1 antibody was raised using a synthetic peptide corresponding to a region with amino acids APYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQD
    Top Product
    Discover our top product PCMT1 Primary Antibody
  • Application Notes
    WB: 2.5 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    PCMT1 Blocking Peptide, catalog no. 33R-1442, is also available for use as a blocking control in assays to test for specificity of this PCMT1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PCMT1 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
    Alternative Name
    PCMT1 (PCMT1 Products)
    Synonyms
    PIMT antibody, C79501 antibody, PCM antibody, PCMT antibody, etID309741.20 antibody, fj13d06 antibody, pimt antibody, wu:fj13d06 antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog antibody, protein-L-isoaspartate(D-aspartate)O-methyltransferase antibody, PCMT1 antibody, Pcmt1 antibody, pcmt1.L antibody, pcmt1 antibody, pcmt antibody
    Background
    Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
    Molecular Weight
    25 kDa (MW of target protein)
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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