Nucleobindin 1 antibody was raised against the C terminal of NUCB1
Purification
Purified
Immunogen
Nucleobindin 1 antibody was raised using the C terminal of NUCB1 corresponding to a region with amino acids PAAHPEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
NUCB1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NUCB1 antibody in PBS
Concentration
Lot specific
Buffer
PBS
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
Target
Nucleobindin 1 (NUCB1)
Alternative Name
Nucleobindin 1
Background
Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer's disease pathogenesis.