Follistatin antibody (C-Term)
Quick Overview for Follistatin antibody (C-Term) (ABIN630158)
Target
See all Follistatin (FST) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- FST antibody was raised against the C terminal of FST
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Purification
- Purified
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Immunogen
- FST antibody was raised using the C terminal of FST corresponding to a region with amino acids SLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN
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Application Notes
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WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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FST Blocking Peptide, catalog no. 33R-8580, is also available for use as a blocking control in assays to test for specificity of this FST antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FST antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Follistatin (FST)
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Alternative Name
- FST
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Background
- Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
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Molecular Weight
- 35 kDa (MW of target protein)
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Pathways
- Negative Regulation of Hormone Secretion
Target
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