SLC11A1 antibody (C-Term)

Catalog No. ABIN630354

The Rabbit Polyclonal anti-SLC11A1 antibody (ABIN630354) specifically detects SLC11A1 in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for SLC11A1 antibody (C-Term) (ABIN630354)

Target: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC11A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC11A1 Antibody

Binding Specificity: C-Term

Specificity: SLC11 A1 antibody was raised against the C terminal of SLC11 1

Purification: Purified

Immunogen: SLC11 A1 antibody was raised using the C terminal of SLC11 1 corresponding to a region with amino acids VLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFT

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SLC11A1 Blocking Peptide, (ABIN5616173), is also available for use as a blocking control in assays to test for specificity of this SLC11A1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SLC10 1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for SLC11A1

Target: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Alternative Name: SLC11A1

Background: SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.

Molecular Weight: 61 kDa (MW of target protein)

Pathways: Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus