HIST1H1C antibody (Middle Region)

Catalog No. ABIN630627

The Rabbit Polyclonal anti-HIST1H1C antibody (ABIN630627) specifically detects HIST1H1C in WB. The antibody is reactive with Human samples.

Quick Overview for HIST1H1C antibody (Middle Region) (ABIN630627)

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H1C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIST1H1C Antibody

Binding Specificity: Middle Region

Specificity: HIST1 H1 antibody was raised against the middle region of HIST1 1

Purification: Affinity purified

Immunogen: HIST1 H1 antibody was raised using the middle region of HIST1 1 corresponding to a region with amino acids ASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKS

Application Details

Application Notes: WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HIST1H1C Blocking Peptide, (ABIN936894), is also available for use as a blocking control in assays to test for specificity of this HIST1H1C antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HIST0 0 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for HIST1H1C

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Alternative Name: HIST1H1C

Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Molecular Weight: 21 kDa (MW of target protein)