GAMT antibody (N-Term)

Catalog No. ABIN631157

The Rabbit Polyclonal anti-GAMT antibody has been validated for WB. It is suitable to detect GAMT in samples from Human.

Quick Overview for GAMT antibody (N-Term) (ABIN631157)

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAMT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GAMT Antibody

Binding Specificity: N-Term

Specificity: GAMT antibody was raised against the N terminal of GAMT

Purification: Affinity purified

Immunogen: GAMT antibody was raised using the N terminal of GAMT corresponding to a region with amino acids MSAPSATPIFAPGENCSPAWGAAPAAYDAADTHLRILGKPVMERWETPYM

Application Details

Application Notes: WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

GAMT Blocking Peptide, (ABIN5613722), is also available for use as a blocking control in assays to test for specificity of this GAMT antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GAMT antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for GAMT

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Alternative Name: GAMT

Background: GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.

Molecular Weight: 26 kDa (MW of target protein)