UBR2 antibody (C-Term)

Catalog No. ABIN631224

This anti-UBR2 antibody is a Rabbit Polyclonal antibody detecting UBR2 in WB. Suitable for Human.

Quick Overview for UBR2 antibody (C-Term) (ABIN631224)

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBR2 Antibody

Binding Specificity: C-Term

Specificity: UBR2 antibody was raised against the C terminal of UBR2

Purification: Affinity purified

Immunogen: UBR2 antibody was raised using the C terminal of UBR2 corresponding to a region with amino acids QGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHAQEANQTLVGIDWQHL

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

UBR2 Blocking Peptide, (ABIN5616890), is also available for use as a blocking control in assays to test for specificity of this UBR2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of UBR2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for UBR2

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Alternative Name: UBR2

Background: Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognise the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.

Molecular Weight: 200 kDa (MW of target protein)