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DCK antibody (Middle Region)

This anti-DCK antibody is a Rabbit Polyclonal antibody detecting DCK in WB. Suitable for Human and Mouse.
Catalog No. ABIN631701

Quick Overview for DCK antibody (Middle Region) (ABIN631701)

Target

See all DCK Antibodies
DCK (Deoxycytidine Kinase (DCK))

Reactivity

  • 51
  • 27
  • 14
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 38
  • 13
  • 3
Rabbit

Clonality

  • 43
  • 11
Polyclonal

Conjugate

  • 36
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DCK antibody is un-conjugated

Application

  • 38
  • 22
  • 22
  • 20
  • 18
  • 11
  • 10
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Specificity

    DCK antibody was raised against the middle region of DCK

    Purification

    Affinity purified

    Immunogen

    DCK antibody was raised using the middle region of DCK corresponding to a region with amino acids QLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQD
  • Application Notes

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    Comment

    DCK Blocking Peptide, (ABIN5613135), is also available for use as a blocking control in assays to test for specificity of this DCK antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DCK antibody in PBS

    Concentration

    Lot specific

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target

    DCK (Deoxycytidine Kinase (DCK))

    Alternative Name

    DCK

    Background

    Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

    Molecular Weight

    30 kDa (MW of target protein)
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