CCDC50 antibody (Middle Region)

Catalog No. ABIN631775

The Rabbit Polyclonal anti-CCDC50 antibody is suitable to detect CCDC50 in samples from Human. It has been validated for WB.

Quick Overview for CCDC50 antibody (Middle Region) (ABIN631775)

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC50 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCDC50 Antibody

Binding Specificity: Middle Region

Specificity: CCDC50 antibody was raised against the middle region of CCDC50

Purification: Affinity purified

Immunogen: CCDC50 antibody was raised using the middle region of CCDC50 corresponding to a region with amino acids KAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPP

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CCDC50 Blocking Peptide, (ABIN939634), is also available for use as a blocking control in assays to test for specificity of this CCDC50 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CCDC50 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for CCDC50

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Alternative Name: CCDC50

Background: CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.

Molecular Weight: 56 kDa (MW of target protein)