YARS antibody (N-Term)

Catalog No. ABIN633610

This Rabbit Polyclonal antibody specifically detects YARS in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for YARS antibody (N-Term) (ABIN633610)

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YARS Antibody

Binding Specificity: N-Term

Specificity: YARS antibody was raised against the N terminal of YARS

Purification: Affinity purified

Immunogen: YARS antibody was raised using the N terminal of YARS corresponding to a region with amino acids MGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKIYWGTATTGKPHV

Application Details

Application Notes: WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

YARS Blocking Peptide, (ABIN5617055), is also available for use as a blocking control in assays to test for specificity of this YARS antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of YARS antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Alternative Name: YARS

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

Molecular Weight: 59 kDa (MW of target protein)