MAP4K2 antibody (N-Term)

Catalog No. ABIN634357

This Rabbit Polyclonal antibody specifically detects MAP4K2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MAP4K2 antibody (N-Term) (ABIN634357)

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP4K2 Antibody

Binding Specificity: N-Term

Specificity: MAP4 K2 antibody was raised against the N terminal of MAP4 2

Purification: Affinity purified

Immunogen: MAP4 K2 antibody was raised using the N terminal of MAP4 2 corresponding to a region with amino acids HLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAE

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MAP4K2 Blocking Peptide, (ABIN939164), is also available for use as a blocking control in assays to test for specificity of this MAP4K2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MAP0 2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for MAP4K2

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Alternative Name: MAP4K2

Background: MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Molecular Weight: 91 kDa (MW of target protein)