Doublecortin antibody

Catalog No. ABIN634473

The Rabbit Polyclonal anti-Doublecortin antibody (ABIN634473) specifically detects Doublecortin in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for Doublecortin antibody (ABIN634473)

Target: Doublecortin (DCX)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Doublecortin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Doublecortin Antibody

Purification: Affinity purified

Immunogen: DCX antibody was raised using a synthetic peptide corresponding to a region with amino acids TAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPIS

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

DCX Blocking Peptide, (ABIN5613146), is also available for use as a blocking control in assays to test for specificity of this DCX antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DCX antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for Doublecortin

Target: Doublecortin (DCX)

Alternative Name: DCX

Background: In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The protein contains two doublecortin domains, which bind microtubules. In addition, DCX interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.

Molecular Weight: 49 kDa (MW of target protein)