IL11RA antibody (N-Term)
Quick Overview for IL11RA antibody (N-Term) (ABIN635796)
Target
See all IL11RA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- IL11 R alpha antibody was raised against the N terminal of IL11 A
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Purification
- Affinity purified
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Immunogen
- IL11 R alpha antibody was raised using the N terminal of IL11 A corresponding to a region with amino acids QLGYPPARPVVSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGAD
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Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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IL11R alpha Blocking Peptide, (ABIN5614167), is also available for use as a blocking control in assays to test for specificity of this IL11R alpha antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL10 A antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
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Alternative Name
- IL11R alpha
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Background
- Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.
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Molecular Weight
- 43 kDa (MW of target protein)
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Pathways
- JAK-STAT Signaling, Growth Factor Binding
Target
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