ST6GALNAC4 antibody (Middle Region)
Quick Overview for ST6GALNAC4 antibody (Middle Region) (ABIN635850)
Target
See all ST6GALNAC4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Specificity
- ST6 GALNAC4 antibody was raised against the middle region of ST6 ALNAC4
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Purification
- Affinity purified
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Immunogen
- ST6 GALNAC4 antibody was raised using the middle region of ST6 ALNAC4 corresponding to a region with amino acids QLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMIL
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Application Notes
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WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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ST6GALNAC4 Blocking Peptide, (ABIN5616408), is also available for use as a blocking control in assays to test for specificity of this ST6GALNAC4 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ST0 ALNAC4 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ST6GALNAC4 (ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 4 (ST6GALNAC4))
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Alternative Name
- ST6GALNAC4
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Background
- ST6GALNAC4 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. ST6GALNAC4 prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. ST6GALNAC4 is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. It is a member of glycosyltransferase family 29.
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Molecular Weight
- 34 kDa (MW of target protein)
Target
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