C2CD2L antibody (C-Term)

Catalog No. ABIN635898

This anti-C2CD2L antibody is a Rabbit Polyclonal antibody detecting C2CD2L in WB. Suitable for Human, Mouse and Rat.

Quick Overview for C2CD2L antibody (C-Term) (ABIN635898)

Target: C2CD2L (C2CD2-Like (C2CD2L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2CD2L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C2CD2L Antibody

Binding Specificity: C-Term

Specificity: TMEM24 antibody was raised against the C terminal Of Tmem24

Purification: Affinity purified

Immunogen: TMEM24 antibody was raised using the C terminal Of Tmem24 corresponding to a region with amino acids AGLSQSHDDLSNATATPSVRKKAGSFSRRLIKRFSFKSKPKANGNPSPQL

Application Details

Application Notes: WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TMEM24 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TMEM24 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TMEM24 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for C2CD2L

Target: C2CD2L (C2CD2-Like (C2CD2L))

Alternative Name: TMEM24

Background: GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

Molecular Weight: 76 kDa (MW of target protein)