Frizzled (AA 1-12) antibody

Catalog No. ABIN636199

This Rabbit Polyclonal antibody specifically detects Frizzled in WB. It exhibits reactivity toward Mouse.

Quick Overview for Frizzled (AA 1-12) antibody (ABIN636199)

Target: Frizzled

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: AA 1-12

Cross-Reactivity (Details): This antibodys immunogen shares 91 % sequence identity with the rat homolog.

Purification: Affinity chromatography purified

Immunogen: Frizzled antibody was raised in rabbit using AA 1-12 [MRGPGTAASHSPC] of murine fz7 as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details

Target: Frizzled

Background: A member of the frizzzled (fz) family, which have been shown to be the transmembrane receptors for the Wnt molecules. Wnts have been implicated in embryonic induction, cell fate determination, control of cell polarity and malignant transformation.

Pathways: WNT Signaling