SHANK1 antibody (C-Term)

Catalog No. ABIN636220

This Rabbit Polyclonal antibody specifically detects SHANK1 in WB and IHC. It exhibits reactivity toward Mammalian.

Quick Overview for SHANK1 antibody (C-Term) (ABIN636220)

Target: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Reactivity: Mammalian

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHANK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SHANK1 Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified

Immunogen: SHANK1 a antibody was raised in rabbit using AA [SGPIYPGLFDIRSS] of the C terminus of the Shank1 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: IHC: 1:100-1:200, WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for SHANK1

Target: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Alternative Name: SHANK1a

Background: Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Pathways: Synaptic Membrane, Maintenance of Protein Location