NFAT1 antibody (AA 269-281)

Catalog No. ABIN636231

This anti-NFAT1 antibody is a Rabbit Polyclonal antibody detecting NFAT1 in WB. Suitable for Human.

Quick Overview for NFAT1 antibody (AA 269-281) (ABIN636231)

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NFAT1 Antibody

Binding Specificity: AA 269-281

Purification: Affinity chromatography purified

Immunogen: NFATc2 antibody was raised in rabbit using AA 269-281 [ASPQRSRSPSPQP] of the human NFATc2 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for NFAT1

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Alternative Name: NFATc2

Background: The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that coordinate the immune response. NFATc is the cytosolic component of NFAT and encoded by a separate gene. Expression of NFATc activates the interleukin (IL-2) promoter in non-T lymphocytes and is required for IL-2 gene expression.

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling