FBXO27 antibody (AA 163-175)

Catalog No. ABIN636302

Product Details anti-FBXO27 Antibody

Target: FBXO27 (F-Box Protein 27 (FBXO27))

Binding Specificity: AA 163-175

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO27 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): This antibodys immunogen shares 76 % sequence identity with the Mouse homolog.

Purification: Affinity chromatography purified

Immunogen: FBG5 antibody was raised in rabbit using AA 163-175 (KKQVLDLEEEGLW) of the human FBG5 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for FBXO27

Target: FBXO27 (F-Box Protein 27 (FBXO27))

Alternative Name: FBG5 (FBXO27 Products)

Background: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.