RANKL antibody

Catalog No. ABIN636595

This Rabbit Polyclonal antibody specifically detects RANKL in WB, ELISA and Inhibition. It exhibits reactivity toward Human.

Quick Overview for RANKL antibody (ABIN636595)

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANKL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Product Details anti-RANKL Antibody

Purification: Purified

Immunogen: OPG antibody was raised in rabbit using highly pure recombinant human OPG (human Osteoprotegerin) as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for RANKL

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Alternative Name: OPG

Background: Osteoprotegerin is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, OPG inhibits nuclear kappa B (NF-kappaB) which is a central and rapid acting transcription factor for immune related genes, and a key regulator of inflammation, innate immunity, cell survival and differentiation.

Molecular Weight: 60-65 kDa (predicted detection band MW)

Pathways: NF-kappaB Signaling