IGFBP7 antibody

Catalog No. ABIN636653

Product Details anti-IGFBP7 Antibody

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: IGF BP7 antibody was raised in rabbit using highly pure recombinant human IGF-BP7 as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Alternative Name: IGF BP7 (IGFBP7 Products)

Synonyms: zgc:85888 antibody, AGM antibody, FSTL2 antibody, IBP-7 antibody, IGFBP-7 antibody, IGFBP-7v antibody, IGFBPRP1 antibody, MAC25 antibody, PSF antibody, RAMSVPS antibody, TAF antibody, Fstl2 antibody, Mac25 antibody, insulin like growth factor binding protein 7 antibody, insulin-like growth factor binding protein 7 antibody, IGFBP7 antibody, igfbp7 antibody, Igfbp7 antibody

Background: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF1n a manner that inhibits IGF1nduced differentiation of skeletal myoblasts, without affecting IGF1nduced proliferation.

Molecular Weight: 26.4 kDa (predicted detection band MW)

Pathways: Growth Factor Binding