GPR3 antibody

Catalog No. ABIN636775

Product Details anti-GPR3 Antibody

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity chromatography purified

Immunogen: GPR3 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Application Details

Application Notes: IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Target Details for GPR3

Target: GPR3 (G Protein-Coupled Receptor 3 (GPR3))

Alternative Name: GPR3 (GPR3 Products)

Synonyms: GPR3 antibody, ACCA antibody, Gpcr3 antibody, Gpcr20 antibody, Gpcr21 antibody, G protein-coupled receptor 3 antibody, G-protein coupled receptor 3 antibody, GPR3 antibody, Gpr3 antibody

Background: GPR3 activates adenylate cyclase in the absence of ligand. GPR3 is expressed in mammalian oocytes where it maintains meiotic arrest and is thought to be a communication link between oocytes and the surrounding somatic tissue. It has been proposed that sphingosine 1-phosphate (S1P) and sphingosylphosphorylcholine (SPC) are GPR3 ligands, however this result was not confirmed in a Beta-arrestin recruitment assay.

Pathways: cAMP Metabolic Process