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THRA antibody
THRA
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-THRA Antibody
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Target
See all THRA Antibodies
THRA
(Thyroid Hormone Receptor, alpha (THRA))
Reactivity
All reactivities for THRA antibodies
Human
Host
All hosts for THRA antibodies
Rabbit
Clonality
All clonalities for THRA antibodies
Polyclonal
Conjugate
All conjugates for THRA antibodies
This THRA antibody is un-conjugated
Application
All applications for THRA antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Affinity chromatography purified
Immunogen
THRA antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Application Details
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Application Notes
IHC-P: 10 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target Details for THRA
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Target
THRA
(Thyroid Hormone Receptor, alpha (THRA))
Alternative Name
THRA (THRA Products )
Background
Thyroid hormone receptor alpha (TR-alpha) also known as nuclear receptor subfamily 1, group A, member 1 (NR1A1), is a nuclear receptor protein that in humans is encoded by the THRA gene. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone.
Pathways
Nuclear Receptor Transcription Pathway , Steroid Hormone Mediated Signaling Pathway , Sensory Perception of Sound , Cellular Response to Molecule of Bacterial Origin , Regulation of Lipid Metabolism by PPARalpha , Regulation of Muscle Cell Differentiation , Maintenance of Protein Location , Skeletal Muscle Fiber Development
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