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PDE8B antibody

PDE8B Reactivity: Human IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN636942
  • Target See all PDE8B Antibodies
    PDE8B (phosphodiesterase 8B (PDE8B))
    Reactivity
    • 15
    • 11
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    This PDE8B antibody is un-conjugated
    Application
    • 13
    • 10
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Affinity chromatography purified
    Immunogen
    PDE8 B antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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    Discover our top product PDE8B Primary Antibody
  • Application Notes
    IHC-P: 5 µg/mL
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
  • Target
    PDE8B (phosphodiesterase 8B (PDE8B))
    Alternative Name
    PDE8B (PDE8B Products)
    Synonyms
    PDE8B antibody, ADSD antibody, PPNAD3 antibody, B230331L10Rik antibody, C030047E14Rik antibody, RNPDE8B antibody, phosphodiesterase 8B antibody, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antibody, PDE8B antibody, LOC100468338 antibody, pde8b antibody, Pde8b antibody
    Background
    Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1-11, PDE4, 7 and 8 selectively degrade cAMP. These enzymes are involved in many signal transduction pathways.
    Pathways
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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