SPEG antibody

Catalog No. ABIN6389343

This Rabbit Polyclonal antibody specifically detects SPEG in IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SPEG antibody (ABIN6389343)

Target: SPEG (SPEG Complex Locus (SPEG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPEG antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SPEG Antibody

Purpose: Unconjugated Rabbit polyclonal to SPEG

Specificity: SPEG Polyclonal Antibody detects endogenous levels of protein.

Purification: SPEG antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype: IgG

Application Details

Application Notes: IHC-p 1:50-300

Comment:

Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC in vivo. In response to vascular injuries ASMC dedifferentiate and change from a quiescent and contractile phenotype to a proliferative and synthetic phenotype. This proliferation of vascular smooth muscle cells is one of the most prominent features of atherosclerosis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for SPEG

Target: SPEG (SPEG Complex Locus (SPEG))

Alternative Name: SPEG

Molecular Weight: 359 kDa

Gene ID: 10290

UniProt: Q15772