MYOC antibody

Catalog No. ABIN6389817

The Rabbit Polyclonal anti-MYOC antibody has been validated for WB and ELISA. It is suitable to detect MYOC in samples from Human, Mouse and Rat.

Quick Overview for MYOC antibody (ABIN6389817)

Target: MYOC (Myocilin (MYOC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MYOC Antibody

Purpose: Unconjugated Rabbit polyclonal to MYOC

Specificity: MYOC Polyclonal Antibody detects endogenous levels of protein.

Purification: MYOC antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Comment:

Detected in aqueous humor . Detected in the eye (at protein level) . Widely expressed. Highly expressed in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart, and bone marrow-derived mesenchymal stem cells. Expressed predominantly in the retina. In normal eyes, found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and seems to be expressed at higher levels than in normal eyes, regardless of the type or clinical severity of glaucoma. The myocilin 35 kDa fragment is detected in aqueous humor and to a lesser extent in iris and ciliary body.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for MYOC

Target: MYOC (Myocilin (MYOC))

Alternative Name: MYOC

Molecular Weight: 55 kDa

Gene ID: 4653

UniProt: Q99972