DMBT1 antibody

Catalog No. ABIN6390433

This anti-DMBT1 antibody is a Rabbit Polyclonal antibody detecting DMBT1 in IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for DMBT1 antibody (ABIN6390433)

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMBT1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DMBT1 Antibody

Purpose: Unconjugated Rabbit polyclonal to DMBT1

Specificity: DMBT1 Polyclonal Antibody detects endogenous levels of protein.

Purification: DMBT1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype: IgG

Application Details

Application Notes: IHC-p 1:50-300

Comment:

Highly expressed in alveolar and macrophage tissues. In some macrophages, expression is seen on the membrane, and in other macrophages, strongly expressed in the phagosome/phagolysosome compartments. Expressed in lung, trachea, salivary gland, small intestine and stomach. In pancreas, expressed in certain cells of the islets of Langerhans. In digestive tract, confined to tissues with large epithelial surfaces. In intestinal tissue, moderately expressed in epithelial cells of the midcrypts and the crypt base. Expression is significantly elevated in intestinal tissue from patients with inflammatory bowel disease (IBD), particularly in surface epithelial and Paneth cells, but not in IBD patients with mutant NOD2. Present in crypt bases of the duodenum, in crypt tops of the colon, and in collecting ducts of the cortical kidney. Expressed in stratified squamous epithelium of vagina and in outer luminar surface and basilar region of columnar epithelial cells in cervix (at protein level). Isoform 1 is secreted to the lumen of the respiratory tract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for DMBT1

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Alternative Name: DMBT1

Molecular Weight: 265 kDa

Gene ID: 1755

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response