DMBT1 antibody

Catalog No. ABIN7190483

Product Details anti-DMBT1 Antibody

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMBT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human DMBT1

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:10-1:50,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DMBT1

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Alternative Name: DMBT1 (DMBT1 Products)

Synonyms: GP340 antibody, muclin antibody, CRP antibody, CRP-[a] antibody, CRP-[b] antibody, Crpd antibody, DBMT1 antibody, gp300 antibody, p80 antibody, DMBT1 antibody, gp340 antibody, deleted in malignant brain tumors 1 antibody, deleted in malignant brain tumors 1 protein antibody, gp340 antibody, deleted in malignant brain tumors 1 S homeolog antibody, DMBT1 antibody, Dmbt1 antibody, LOC100064515 antibody, dmbt1 antibody, ST201phi2-1p340 antibody, dmbt1.S antibody

Background:

Background: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.

Aliases: Apactin antibody, CRP antibody, CRP-[a] antibody, CRP-[b] antibody, CRP-ductin antibody, Crpd antibody, DBMT1 antibody, Deleted in malignant brain tumors 1 antibody, Deleted in malignant brain tumors 1 protein antibody, DMBT 1 antibody, DMBT1 antibody, DMBT1 prototype precursor antibody, DMBT1/6kb.1 protein precursor antibody, DMBT1/8kb.1 protein antibody, DMBT1/8kb.2 protein precursor antibody, DMBT1_HUMAN antibody, Ebnerin antibody, FLJ61058 antibody, Glycoprotein 300 antibody, Glycoprotein 340 antibody, Gp 340 antibody, Gp-340 antibody, gp300 antibody, GP340 antibody, Gp340 variant protein antibody, Hensin antibody, MGC164738 antibody, Mucin-like glycoprotein antibody, Muclin antibody, OTTHUMP00000020654 antibody, OTTHUMP00000020655 antibody, OTTHUMP00000020656 antibody, OTTHUMP00000020657 antibody, OTTHUMP00000020658 antibody, OTTHUMP00000020659 antibody, OTTHUMP00000020660 antibody, OTTHUMP00000020661 antibody, OTTHUMP00000020662 antibody, OTTHUMP00000020663 antibody, p80 antibody, Pancrin antibody, SAG antibody, Salivary agglutinin antibody, Surfactant pulmonary associated D binding protein antibody, Surfactant pulmonary associated protein D binding protein antibody, Surfactant pulmonary-associated D-binding protein antibody, Vomeroglandin antibody

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response