CD52 antibody

Catalog No. ABIN640679

Product Details anti-CD52 Antibody

Target: CD52

Reactivity: Human

Host: Rat

Conjugate: This CD52 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytotoxicity Test (CyTox), Immunoprecipitation (IP), Immunohistochemistry (Resin Sections) (IHC (rs))

Specificity: This product reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small peptide that is heavily glycosylated, and attached to the cell surface membrane via a GPI link. The apparent molecular mass of the antigen on SDS-PAGE is 25-29kD. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanized versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies.

Cross-Reactivity: Rhesus Monkey

Characteristics: Rat Anti-Human CD52, low endotoxin

Isotype: IgG2b

Application Details

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Storage: -20 °C

Target Details for CD52

Target: CD52

Alternative Name: CD52 (CD52 Products)

Background: Synonyms: CDW52, HE5