2B4 antibody

Catalog No. ABIN642494

Product Details anti-2B4 Antibody

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This 2B4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Purpose: Mouse Anti-Human CD244, low endotoxin

Specificity: DS-MB-00535 is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

Characteristics: Adhesion Molecule/Cell Surface

Endotoxin Level: Low Endotoxin

Immunogen: CD244 Fusion protein

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Immunoprecipitation

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details for 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Alternative Name: CD244 (CD244 Products)