ICAM1 antibody

Catalog No. ABIN643798

This Mouse Monoclonal antibody specifically detects ICAM1 in FACS, IP, IF, IHC (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for ICAM1 antibody (ABIN643798)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ICAM1 Antibody

Purpose: Mouse Anti-Rat CD54

Specificity: DS-MB-00820 recognizes the rat CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1), a 90kD adhesion molecule belonging to the immunoglobulin superfamily. CD54 is a cell surface ligand of the lymphocyte integrin, LFA-1 and is known to play an important role in various cell-cell interactions in the immune system. Recent studies suggest that cross-linking of ICAM-1 using clone DS-MB-00820 induces calcium signalling (4). Functionally DS-MB-00820 inhibits homotypic aggregation of PHA blasts.

Characteristics: Adhesion Molecule/Cell Surface

Purification: Purified

Immunogen: Rat Ax cells (a HEV derived cell line)

Isotype: IgG1

Application Details

Application Notes: Immunohistology - Frozen, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunohistology - Paraffin

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: CD54

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling