PIGM antibody (C-Term)

Catalog No. ABIN650949

This anti-PIGM antibody is a Rabbit Polyclonal antibody detecting PIGM in WB, FACS and IHC (p). Suitable for Human.

Quick Overview for PIGM antibody (C-Term) (ABIN650949)

Target: PIGM (Phosphatidylinositol Glycan M (PIGM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB25415

Product Details anti-PIGM Antibody

Binding Specificity: AA 394-423, C-Term

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PIGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human PIGM.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PIGM

Target: PIGM (Phosphatidylinositol Glycan M (PIGM))

Alternative Name: PIGM

Background: PIGM encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGM encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.

Molecular Weight: 49460

Gene ID: 93183

NCBI Accession: NP_660150

UniProt: Q9H3S5

Pathways: Inositol Metabolic Process, Cellular Glucan Metabolic Process