FBXL2 antibody (C-Term)

Catalog No. ABIN651220

This Rabbit Polyclonal antibody specifically detects FBXL2 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FBXL2 antibody (C-Term) (ABIN651220)

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB30004

Product Details anti-FBXL2 Antibody

Binding Specificity: AA 366-395, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBXL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-395 amino acids from the C-terminal region of human FBXL2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000-1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for FBXL2

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Alternative Name: FBXL2

Background: FBXL2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.

Molecular Weight: 47062

Gene ID: 25827

NCBI Accession: NP_001165184, NP_036289

UniProt: Q9UKC9