RDH16 antibody (N-Term)

Catalog No. ABIN651647

The Rabbit Polyclonal anti-RDH16 antibody is suitable to detect RDH16 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for RDH16 antibody (N-Term) (ABIN651647)

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDH16 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB26396

Product Details anti-RDH16 Antibody

Binding Specificity: AA 3-31, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RDH16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-31 amino acids from the N-terminal region of human RDH16.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for RDH16

Target: RDH16 (Retinol Dehydrogenase 16 (All-Trans) (RDH16))

Alternative Name: RDH16

Background: Retinol dehydrogenase 16 (RDH16) is an oxidoreductase with a preference for NAD. It oxidizes all-trans-retinol and 13-cis-retinol to the corresponding aldehydes. RDH16 has higher activity towards CRBP-bound retinol than with free retinol. It oxidizes 3-alpha-hydroxysteroids and also oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. RDH16 can also catalyze the reverse reaction.

Molecular Weight: 35673

Gene ID: 8608

NCBI Accession: NP_003699

UniProt: O75452

Pathways: Steroid Hormone Biosynthesis