NDST2 antibody (AA 817-844)

Catalog No. ABIN2840469

Product Details anti-NDST2 Antibody

Target: NDST2 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2))

Binding Specificity: AA 817-844

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDST2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NDST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-844 amino acids of human NDST2.

Clone: RB21472

Isotype: IgG

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-NDST2 antibody (ABIN2840469)

Datta, Yang, Linhardt, Sharfstein: "Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells." in: Cytotechnology, Vol. 67, Issue 2, pp. 223-35, (2015) (PubMed).

Gasimli, Glass, Datta, Yang, Li, Gemmill, Baik, Sharfstein, Esko, Linhardt: "Bioengineering murine mastocytoma cells to produce anticoagulant heparin." in: Glycobiology, Vol. 24, Issue 3, pp. 272-80, (2014) (PubMed).

Datta, Li, Yang, Zhao, Baik, Gemmill, Sharfstein, Linhardt: "Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site." in: The Journal of biological chemistry, Vol. 288, Issue 52, pp. 37308-18, (2013) (PubMed).

Target Details for NDST2

Target: NDST2 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2))

Alternative Name: NDST2 (NDST2 Products)

Background: NDST2 is a member of the N-deacetylase/N-sulfotransferase subfamily of the sulfotransferase 1 proteins. The encoded enzyme has dual functions in processing glucosamine and heparin polymers, including N-deacetylation and N-sulfation. The encoded protein may be localized to the Golgi.

Molecular Weight: 100875

Gene ID: 8509

NCBI Accession: NP_003626

UniProt: P52849

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process