BRDT antibody (N-Term)

Catalog No. ABIN652290

This anti-BRDT antibody is a Rabbit Polyclonal antibody detecting BRDT in WB. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for BRDT antibody (N-Term) (ABIN652290)

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRDT antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB8492

Product Details anti-BRDT Antibody

Binding Specificity: AA 1-30, N-Term

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BRDT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BRDT.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-BRDT antibody (ABIN652290)

Li, Sha, Wang, Li, Wang, Kee, Wang: "Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa." in: Oncotarget, Vol. 8, Issue 12, pp. 19914-19922, (2017) (PubMed).

Target Details for BRDT

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Alternative Name: BRDT

Background: BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.

Molecular Weight: 107954

Gene ID: 676

NCBI Accession: NP_001229734, NP_001229735, NP_001229736, NP_001229737, NP_001229739, NP_001717, NP_997072

UniProt: Q58F21