TrkA-pY791 (AA 769-796) antibody

Catalog No. ABIN652381

This Rabbit Polyclonal antibody specifically detects TrkA-pY791 in FACS, WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for TrkA-pY791 (AA 769-796) antibody (ABIN652381)

Target: TrkA-pY791

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB16572

Product Details

Binding Specificity: AA 769-796

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TrkA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 769-796 amino acids from human TrkA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: TrkA-pY791

Background: TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Molecular Weight: 87497

Gene ID: 4914

NCBI Accession: NP_001007793, NP_001012331, NP_002520

UniProt: P04629