MAP3K13 antibody (C-Term)

Catalog No. ABIN652423

This Rabbit Polyclonal antibody specifically detects MAP3K13 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MAP3K13 antibody (C-Term) (ABIN652423)

Target: MAP3K13 (Mitogen-Activated Protein Kinase Kinase Kinase 13 (MAP3K13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB12383

Product Details anti-MAP3K13 Antibody

Binding Specificity: AA 854-884, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAP3K13 (LZK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 854-884 amino acids from the C-terminal region of human MAP3K13 (LZK).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MAP3K13

Target: MAP3K13 (Mitogen-Activated Protein Kinase Kinase Kinase 13 (MAP3K13))

Alternative Name: MAP3K13 (LZK)

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

Molecular Weight: 108296

Gene ID: 9175

NCBI Accession: NP_001229243, NP_001229246, NP_004712

UniProt: O43283

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2