MAP3K13 antibody (AA 120-200)

Catalog No. ABIN7215656

This Rabbit Polyclonal antibody specifically detects MAP3K13 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MAP3K13 antibody (AA 120-200) (ABIN7215656)

Target: MAP3K13 (Mitogen-Activated Protein Kinase Kinase Kinase 13 (MAP3K13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MAP3K13 Antibody

Binding Specificity: AA 120-200

Purpose: Rabbit Anti-LZK Polyclonal Antibody

Specificity: LZK Polyclonal Antibody detects endogenous levels of LZK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human LZK at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAP3K13

Target: MAP3K13 (Mitogen-Activated Protein Kinase Kinase Kinase 13 (MAP3K13))

Alternative Name: LZK

Background: MAP3K13, LZK, Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLKMitogen-activated protein kinase kinase kinase 13 encoded by MAP3K13 is a member of serine/threonine protein kinase family. Mitogen-activated protein kinase kinase kinase 13 contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. Mitogen-activated protein kinase kinase kinase 13 can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.

Molecular Weight: 108kD

Gene ID: 9175

UniProt: O43283

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2