NPPA antibody (N-Term)

Catalog No. ABIN652474

This Rabbit Polyclonal antibody specifically detects NPPA in WB, IHC (p) and FACS. It exhibits reactivity toward Human and Mouse and has been mentioned in 2+ publications.

Quick Overview for NPPA antibody (N-Term) (ABIN652474)

Target: NPPA (Natriuretic Peptide A (NPPA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB22001

Product Details anti-NPPA Antibody

Binding Specificity: AA 30-56, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NPPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-56 amino acids from the N-terminal region of human NPPA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-NPPA antibody (ABIN652474)

Fernandez-Perez, Munshi: "Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts." in: Journal of visualized experiments : JoVE, Issue 121, (2018) (PubMed).

Nam, Lubczyk, Bhakta, Zang, Fernandez-Perez, McAnally, Bassel-Duby, Olson, Munshi: "Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors." in: Development (Cambridge, England), Vol. 141, Issue 22, pp. 4267-78, (2014) (PubMed).

Target Details for NPPA

Target: NPPA (Natriuretic Peptide A (NPPA))

Alternative Name: NPPA

Background: NPPA belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor(containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity.

Molecular Weight: 16396

Gene ID: 4878

NCBI Accession: NP_006163

UniProt: P01160