TRIB2 antibody (N-Term)

Catalog No. ABIN652876

This Rabbit Polyclonal antibody specifically detects TRIB2 in WB, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for TRIB2 antibody (N-Term) (ABIN652876)

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB9215

Product Details anti-TRIB2 Antibody

Binding Specificity: AA 1-30, N-Term

Predicted Reactivity: B, M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This TRIB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TRIB2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TRIB2

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Alternative Name: TRIB2

Background: TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.

Molecular Weight: 38801

Gene ID: 28951

NCBI Accession: NP_067675

UniProt: Q92519