COX IV antibody (N-Term)

Catalog No. ABIN653098

This Rabbit Polyclonal antibody specifically detects COX IV in WB and IHC (p). It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for COX IV antibody (N-Term) (ABIN653098)

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX IV antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23257

Product Details anti-COX IV Antibody

Binding Specificity: AA 25-54, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COX4I1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human COX4I1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-COX IV antibody (ABIN653098)

Huang, Zhan, Cao, Li, Lyu, Guo, Zhang, Ji, Ren, An, Liu, Nie, Xing: "Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways." in: Autophagy, Vol. 12, Issue 6, pp. 999-1014, (2017) (PubMed).

Target Details for COX IV

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Alternative Name: COX4I1

Background: COX4I1 is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Molecular Weight: 19577

Gene ID: 1327

NCBI Accession: NP_001852

UniProt: P13073

Pathways: Proton Transport