Lactate Dehydrogenase A antibody (AA 154-182)

Catalog No. ABIN653476

This Rabbit Polyclonal antibody specifically detects Lactate Dehydrogenase A in WB, IHC (p) and FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Lactate Dehydrogenase A antibody (AA 154-182) (ABIN653476)

Target: Lactate Dehydrogenase A (LDHA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lactate Dehydrogenase A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB24077

Product Details anti-Lactate Dehydrogenase A Antibody

Binding Specificity: AA 154-182

Predicted Reactivity: B, Pr, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the Central region of human LDHA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Lactate Dehydrogenase A antibody (ABIN653476)

Rueda, Johnson, Giddabasappa, Swaroop, Brooks, Sigel, Chaney, Fox: "The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases." in: Molecular vision, Vol. 22, pp. 847-85, (2016) (PubMed).

Target Details for Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Alternative Name: LDHA

Background: LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.

Molecular Weight: 36689

Gene ID: 3939

NCBI Accession: NP_001128711, NP_001158886, NP_001158887, NP_001158888, NP_005557

UniProt: P00338

Pathways: Warburg Effect