PLB-T17 (AA 1-30) antibody

Catalog No. ABIN653840

The Rabbit Polyclonal anti-PLB-T17 antibody is suitable to detect PLB-T17 in samples from Human, Mouse and Rat. It has been validated for WB, FACS and IHC (p).

Quick Overview for PLB-T17 (AA 1-30) antibody (ABIN653840)

Target: PLB-T17

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB24137

Product Details

Binding Specificity: AA 1-30

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PLB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids of human PLB.

Isotype: IgG

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: PLB-T17

Background: PLB is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases, whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Molecular Weight: 6109

Gene ID: 5350

NCBI Accession: NP_002658

UniProt: P26678